school

Dr. Simon C. Body, MBChB, MPH
Associate Professor
Harvard Medical School

Brigham and Women's Hospital
Department of Anesthesiology, Perioperative and Pain Medicine
75 Francis Street, CWN L1
Boston, MA 02115

Phone: (617) 732-8217
Fax: (617) 730-2813

body@zeus.bwh.harvard.edu

MEET OUR TEAM
INVESTIGATORS:
Dr. Simon Body
Dr. Ronen Durst
Dr. Mahyar Heydarpour
Dr. Robert Levine
Dr. Christine Seidman
Dr. Jon Seidman
Dr. Stan Shernan
Dr. Susan Slaugenhaupt
STAFF:
Dr. Kujtim Bodinaku
Ms. Svetlana Gorbatov
Mr. James Gosnell
Ms. Adrienne Kicza
Ms. Barbara McDonough
Ms. Leah Rastiello
Ms. Elizabeth Sparks

Simon C. Body, M.B.,Ch.B., M.P.H., is Associate Professor of Anesthesia at Harvard Medical School and a Cardiac Anesthesiologist at Brigham and Women’s Hospital. His academic interest is the role of genetic variation upon postoperative outcomes after cardiac surgery. In addition he is particularly interested in the role of genetic variation in bicuspid aortic valve disease.

Education / Training
Medical School: Auckland Medical School, Auckland, New Zealand
Residencies / Fellowships: Auckland Hospital, Auckland, New Zealand and Brigham & Women's Hospital, Boston, MA

Research focus:
The effect of genetic variation upon outcomes after cardiac surgery and the role of genetic variation in bicuspid aortic valve disease

Representative Publications:
Liu KY, Muehlschlegel JD, Perry TE, Fox AA, Collard CD, Body SC, Shernan SK. Common genetic variants on chromosome 9p21 predict perioperative myocardial injury after coronary artery bypass graft surgery. J Thorac Cardiovasc Surg. 2009 Oct 9. [Epub ahead of print] PubMed PMID: 19819472.

Aranki SF, Body SC. Antiplatelet agents used for early intervention in acute coronary syndrome: myocardial salvage versus bleeding complications. J Thorac Cardiovasc Surg. 2009 Oct;138(4):807-10. PubMed PMID: 19769880.

Perry TE, Muehlschlegel JD, Liu KY, Fox AA, Collard CD, Body SC, Shernan SK; CABG Genomics Investigators. C-Reactive protein gene variants are associated with postoperative C-reactive protein levels after coronary artery bypass surgery. BMC Med Genet. 2009 May 8;10:38. PubMed PMID: 19426506; PubMed Central PMCID: PMC2686694.

Muehlschlegel JD, Perry TE, Liu KY, Nascimben L, Fox AA, Collard CD, Avery EG, Aranki SF, D'Ambra MN, Shernan SK, Body SC; CABG Genomics Investigators. Troponin is superior to electrocardiogram and creatinine kinase MB for predicting clinically significant myocardial injury after coronary artery bypass grafting. Eur Heart J. 2009 Jul;30(13):1574-83. Epub 2009 Apr 30. PubMed PMID: 19406870; PubMed Central PMCID: PMC2733736.

Fox AA, Collard CD, Shernan SK, Seidman CE, Seidman JG, Liu KY, Muehlschlegel JD, Perry TE, Aranki SF, Lange C, Herman DS, Meitinger T, Lichtner P, Body SC. Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting. Anesthesiology. 2009 Apr;110(4):738-47. PubMed PMID: 19326473; PubMed Central PMCID: PMC2735337.

Fox AA, Shernan SK, Collard CD, Liu KY, Aranki SF, DeSantis SM, Jarolim P, Body SC. Preoperative B-type natriuretic peptide is as independent predictor of ventricular dysfunction and mortality after primary coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2008 Aug;136(2):452-61. PubMed PMID: 18692657; PubMed Central PMCID: PMC2739747.

Muehlschlegel JD, Body SC. Impact of genetic variation on perioperative bleeding. Am J Hematol. 2008 Sep;83(9):732-7. Review. PubMed PMID: 18508320.

Collard CD, Shernan SK, Fox AA, Bernig T, Chanock SJ, Vaughn WK, Takahashi K, Ezekowitz AB, Jarolim P, Body SC. The MBL2 'LYQA secretor' haplotype is an independent predictor of postoperative myocardial infarction in whites undergoing coronary artery bypass graft surgery. Circulation. 2007 Sep 11;116(11 Suppl):I106-12. PubMed PMID: 17846289.

BAV Genetics

email: contact@bav-genetics.org

Brigham and Women's Hospital
75 Francis Street
Boston, MA 02115

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